It’s All About
the Dose.
How one parameter shapes the entire plant protection regulatory dossier — and why the effects are often not what you would expect.
Built for everyone
who works with PPP dossiers.
Whether you are just entering the regulatory world or have years of experience in a specific area, this course gives you a complete picture of how dose and concentration affect every section of a plant protection product dossier.
It is particularly valuable for professionals who work in one area of the dossier and want to understand how their work connects to — and is affected by — decisions made elsewhere.
Marketing & Product Management
Understand the regulatory implications of dose decisions before they reach your regulatory team — and avoid costly surprises.
Efficacy & Field Trial Professionals
See how the doses you test in the field ripple through the entire dossier — from residues to environmental exposure.
Regulatory Professionals (all levels)
Build a complete cross-disciplinary view of the dossier — essential for junior professionals and a valuable refresh for experienced ones.
A complete picture of the dossier —
through the lens of dose.
Understand all dossier sections
Get a clear overview of every section of a PPP dossier — physico-chemical properties, residues, toxicology, ecotoxicology, and efficacy.
See how dose connects everything
Understand how changes in dose and concentration propagate through the entire dossier — often in ways that are far from obvious.
Learn from real case studies
Analyse real regulatory cases where dose effects were counterintuitive — including products where 2-year studies had to be repeated.
Make better regulatory decisions
Apply cross-disciplinary thinking to your own regulatory work — whether in marketing, field trials, or regulatory affairs.
Communicate across disciplines
Speak the language of every dossier section — and understand the constraints and concerns of colleagues in other areas.
Spot counterintuitive risks early
Recognise the dose-related traps that catch even experienced regulatory professionals — before they become dossier problems.
Course structure.
Why This Course
Why dose is the single most important parameter in a PPP dossier — and why its effects across dossier sections are systematically underestimated.
Physico-Chemical Properties
How dose and formulation concentration affect physicochemical characterisation and what this means for downstream assessments.
Residues
The relationship between application dose, field trial design, and MRL setting — including how dose changes can trigger new supervised residue trials.
Toxicology
How dose affects operator, worker, bystander and resident exposure assessments — and the conditions under which 2-year studies need to be repeated.
Ecotoxicology
The impact of dose on environmental exposure and risk assessment for aquatic organisms, birds, mammals, bees, and soil organisms.
“Efficacy Against Everything”
How efficacy data and label claims interact with dose — and the regulatory implications of changing application rates after authorisation.
When the dose surprises you.
The water volume that rejected a product
A product that passed all toxicological and environmental assessments — but was rejected because of the volume of water used in application. A counterintuitive case that changed how we think about spray concentration.
LWA and dose per hectare
How the relationship between label water allowance and dose per hectare creates regulatory traps — and why getting this wrong can invalidate years of trial data.
And more…
Additional real-world cases from toxicology, residues, and ecotoxicology — including products where small dose changes triggered the need to repeat multi-year studies.
Flexible delivery,
practical content.
4 hours
Compact and focused — designed to deliver maximum value without taking you away from work for days.
Online
Self-paced online delivery with video lessons, slides, and downloadable materials.
In-person
Available as an in-person workshop for teams and organisations. Contact us for group bookings.
English / Italian
Available in both English and Italian — choose your preferred language at enrolment.
Taught by the person
who lived these cases.
I am Stefano Ravagli, founder of Euregulator. The case studies in this course are not hypothetical — they are real regulatory situations I encountered during decades of work in EU plant protection regulatory affairs.
I designed this course because I kept seeing the same mistakes made by talented professionals who had deep expertise in one area of the dossier but lacked the cross-disciplinary view to anticipate how dose decisions would affect everything else.
Four hours with this course can save you — or your company — months of rework.
Join the waitlist.
Get early access + 10% off.
This course is launching in 2026. Join the waitlist now and receive early access plus a 10% discount at launch — and be notified as soon as enrolment opens.